EPA Proposes Updates to TSCA Chemical Review Process

The Environmental Protection Agency (EPA) has proposed a new rule to change how it evaluates the safety of chemicals that are already in commerce under the Toxic Substances Control Act (TSCA). According to EPA Administrator Lee Zeldin, the goal is to provide a clearer, more predictable process that protects both human health and the environment. This also aims to give businesses more clarity on how chemical reviews will be handled.

Key Proposed Changes

EPA’s proposal includes making amendments to the 2024 Risk Evaluation Framework Rule (aka TSCA Risk Evaluation Process):

• Risk determinations by condition of use: Instead of a single finding for a chemical substance as a whole, EPA would make separate determinations for each use of the chemical.
• Recognition of workplace controls: The rule clarifies how EPA will consider personal protective equipment (PPE) and engineering controls in evaluating occupational exposures.
• Scope flexibility: EPA may use discretion in deciding which conditions of use, exposure routes, and pathways are included in a risk evaluation.
• Updated definitions: To better align with Executive Order 14303 and enhance transparency.
• Procedural improvements: To help EPA meet statutory deadlines and streamline revisions or enhancements to risk evaluations.
• Manufacturer obligations: Proposed updates would refine how manufacturers (including importers) request EPA-conducted risk evaluations.

For manufacturers, importers, and users, these changes could mean more detailed risk evaluations of chemicals, clarification on when PPE and other controls factor into EPA’s decisions, and shifts in data collection and reporting.

The EPA is accepting public comments on this proposed rule under docket EPA-HQ-OPPT-2025-0260 until November 7, 2025.

How Walden Can Help

Navigating the ever-changing TSCA requirements can be challenging. Walden’s team of EHS professionals tracks regulatory developments closely and can:

• Help with reviewing chemical inventory and use
• Identify potential regulatory impacts
• Provide guidance on compliance
• Assist with employee training
• And more!

If your business manufactures, imports, or uses chemicals, Walden can help you understand what this proposed rule means for you and ensure you stay ahead of compliance obligations.

Contact our EHS team at 860-846-4069 to discuss your needs with an experienced safety specialist.